Immunocal/HMS90 Questions and Answers
Q. What is Immunocal®? What is HMS-90®?
A. Immunocal® is known as HMS90® in Canada. This unique product is manufactured by Immunotec Research in Montreal, Canada. It is not a prescription drug, but a powerful and patented un-denatured and highly bioactive whey protein dietary supplement that is loaded with glutathione precursors. Immunocal® took $10 million and 18 years of research to perfect. It is unique in the nutritional field as it is covered by10 ‘Method of Use’ patents worldwide: 5 in the US, 3 in Canada and 2 in Australia. Immunocal® is a highly concentrated milk serum isolate which is high in protein (90% protein by weight) and is lactose-free and fat-free. Immunocal® shares many of the same immune promoting andenhancing properties of Mother’s milk. Immunocal® has been clinically proven to increase serum and tissue glutathione levels, and its efficacy is validated by extensive research, including over 450 that appear in the medical literature. These scientific papers can be examined through MEDLINE (the US National Library of Medicine). Immunocal® increases glutathione which is your cells’ own natural antioxidant and mostpotent detoxifier. Immunocal® has been demonstrated to enhance both healthy and deficient immune systems, and is validated as an effective nutritional supplement by the medical community. Immunocal® has its own NDC (National Drug Control) number, and is reimbursable under Medicaid, Medicare, and by private insurance in many states.
Q. Can children take Immunocal?
A. Yes they certainly can. There is no problem with side effects or worry about conflicts with medication. Children should be given 11/4 teaspoon of Immunocal for every 3 lbs of body weight.
Q. What is the difference between Immunocal and other whey proteins?
A. Immunocal has been shown to differ from other whey proteins in its effect upon the immune system. Specifically, scientific studies on otherwhey proteins have not shown the same immune stimulating effects that are seen with Immunocal®. Immunocal has been extensively studied in the clinical literature. Comparing the bioactive ingredients in Immunocal to those in other whey proteins clearly shows the superiority of Immunocal®. Immunocal is a bioactive dietary supplement that is supported by eighteen years of research through rigorous clinical trials that have been published in peer review journals. These studies, performed in world-renowned medical and scientific institutions, attest to the efficacy of Immunocal. Immunocal studies have shown that Immunocal not only increases intracellular levels of GSH (glutathione or glutathione precursors) following ingestion, but also significantly builds up the stores of these substances inside the cells. This beneficial effect lasts for considerable periods of time after ingestion of Immunocal.
Q. What is the product’s bioactivity dependent upon?
A. Concentrations of 3 bioactive and thermo labile (easily damaged by heat) proteins that are contained in the milk serum: serum albumin, alpha lactalbumin and lactoferrin. Because these compounds can be damaged by heat (in excess of 140 degrees F) or excessive mechanical agitation, Immunocal® must not be cooked, heated, or placed in a steel-bladed blender. For these reasons, and to preserve the bioactivity of itsserum albumin, alpha lactalbumin and lactoferrin, Immunocal® has not been exposed to standard high-temperature Pasteurization. Rather, ithas been bio-filtered to remove bacteria, and subjected to a patented process of low-temperature purification procedures to ensure its safety andpurity.
Q. If a different manufacturer of whey protein supplements was able to duplicate our
technology, could they make the same claims?
A. No. The power of our patents is not in manufacturing. Immunocal patents (presently there are ten patents on Immunocal®: 5 US patents, 3Canadian and 2 Australian patents relate to the METHOD OF USE. That is, no other whey protein can state: “clinically PROVEN to stimulate theimmune system”, and “significantly raises glutathione levels”. Additionally, although there are dozens of companies producing DENATURED(high-heat Pasteurized) whey proteins (primarily for use as a protein source in body-building), there currently is no company manufacturing anUNDENATURED whey protein product similar to Immunocal. Over 450 clinical studies and medical reviews appear in the clinical literature which specifically involved Immunocal®, and not other whey proteins. Accept no imitations.
Q. What exactly is glutathione (GSH) and how is it important?
A. Glutathione is the master antioxidant of the body. Without glutathione, we would die. The replenishment of the glutathione levels within thelymphocytes (also called leukocytes or white blood cells) increases the intensity of the immune response. The increase in glutathione levels also results in the proliferation of lymphocytes that act as scavengers, and helps to combat infections. Selenium is a structural component of, and a co-factor for the antioxidant enzyme glutathione peroxidase. For this reason, supplementation with selenium can modestly increase glutathione levels in persons who are selenium deficient. Glutathione is a tri-peptide of the amino acids cysteine, glycine, and glutamic acid. Tissue glutathione levels increase when cystine levels increase within the cell. This is why cystine is critical in the production of glutathione. Prior to the development of Immunocal, no effective way was known to safely and significantly increase cystine levels in the cell over long periods of time. A deficiency of glutathione can cause haemolysis (the destruction of red blood cells resulting in severe anaemia) and numerous diseases of oxidative stress. Glutathione is essential in intermediary metabolism as a donor of sulfhydryl groups that are essential for the detoxification of the liver. The antioxidant enzyme glutathione peroxidase functions in the process of elimination of wastes from the body. Glutathione works within the liver, lungs, colon, kidneys, and skin in the process of removing toxic cellular metabolic wastes.
Q. What is the difference between products or pills that people use as supplements that are
labeled as “glutathione” or “cystine”?
A. Glutathione must be produced within the cells (intra-cellularly). Clinical and laboratory studies demonstrate that oral glutathione is NOT absorbed but will be eliminated by the liver through the bile before ever reaching the systemic circulation (blood stream). Several studies havesuggested that supplementing with oral glutathione may actually do the reverse and depress cellular and blood levels of glutathione. Injectable glutathione also has limited benefits. It is unstable in the blood stream. By the time it reaches the cell, much of it has been degraded, and much of the remaining glutathione cannot effectively pass through the cell membrane. Cystine is not well absorbed when taken by mouth. Clinical studies have demonstrated that oral cystine supplementation (NAC or N Acetyl L- Cysteine) is not effective in increasing cystine levels within the cell, and also has not been associated with significant increases in glutathione levels within the cell. The three bioactive proteins supplied by Immunocal constitute a “natural delivery system” from these cystine precursors to the cell (in order to facilitate clinically and statistically significant increases in glutathione levels in BOTH the extracellular serum and intracellular tissues). Because Immunocal® provides the building blocks for cystine, and these building blocks for cystine are easily transported inside the cell where they can be quickly synthesized into glutathione, Immunocal® is therefore ideally suited to increase glutathione levels within the cell.
Q. What are some additional benefits of un-denatured whey proteins?
A. Immunocal® has been clinically demonstrated to increase exercise capacity by 13 percent (Lands et al., 1999), and may be useful as asupplement for competitive athletes. Wattanabe et al. (Japan) conducted a clinical study with Immunocal to evaluate increases in GSH among patients with Hepatitis B and C, and found that these viruses are vulnerable to glutathione. In-vitro studies in Japan also showed that whey could stimulate the bone cell (osteoblasts) to produce more bone, hence increasing bone density and reducing the risk of osteoporosis. Lactalbumin from whey protein has been demonstrated to kill breast cancer cells in-vitro. Glutathione (from whey protein) lowers serumcholesterol by stimulating bile synthesis in the liver. In addition, glutathione is a powerful antioxidant that will prevent lipid peroxidation (a sign of free radical activity). Lipid peroxidation is implicated in arteriosclerosis (hardening of the arteries), stroke and coronary artery disease.
Q. How does the manufacturing of our product differ from other whey proteins?
A. In the manufacturing of other whey proteins several things occur: in the process of heating and Pasteurization, critical bonds holding thecystine together get broken down (“denatured”, meaning they lose their original nature–similar to the denaturing and irreversible changing ofliquid egg white by the heating process involved in frying an egg). The exact type of proteins that serve to increase tissue and serum glutathione most effectively are lost or diminished. The researchers at Immunotec (the manufacturers of Immunocal®) have developed a process by which these delicate proteins remain intact in their natural form to serve us most effectively.
Q. What is the theoretical mechanism of action of GLUTATHIONE (GSH) in Cancer and
A. Natural killer (Immune) cells may become glutathione-depleted over time, and their immune response weakens. Immunocal raises glutathione levels and strengthens the immune system to fight cancer, viruses, bacteria, etc. For those patients receiving traditional medicaltherapy for their cancers, Immunocal supplies lactalbumin and has been clinically proven to raise glutathione levels. Glutathione and lactalbumin (a component of Immunocal®) have been associated with the strengthening of healthy cells and (paradoxically) the weakening of cancerous cells. In research conducted by C. Svanborg et al, lactalbumin was associated with apoptosis (or the programmed death) of breastcancer cells. Glutathione has been scientifically demonstrated to decrease cancerous cells’ resistance to chemotherapeutic drugs, while protecting healthy cells. This should allow a patient to respond better to chemotherapy with fewer side effects.
Q. What are the diseases or conditions that have been associated with low glutathione
A. There are over 100 diseases and conditions associated with low glutathione levels. Most of the degenerative diseases of aging and the autoimmune diseases have been studied and linked to low GSH levels including: Acetaminophen poisoning, ADD, Addison’s disease, aging, AIDS, alopecia areata, ALS, Alzheimer’s’ disease, anaemia (haemolytic), ankylosing spondylitis, arteriosclerosis (hardening of the arteries), arthritis (rheumatoid), asthma, autism, autoimmune disease, burns, cacexia, cancer, candidainfection, cardiomyopathy (idiopathic), Chronic Fatigue Syndrome, colitis, coronary artery disease, cystic fibrosis, diabetes, Crohn’s disease, eczema, emphysema, Epstein Barr Viral (EBV) syndrome, fibromyalgia, free radical overload, Graves’ disease, hepatic dysfunction (liver disease), hepatitis B, hepatitis C, hypercholesterolemia (high blood cholesterol), herpes, infections (viral, bacterial and fungal), inflammatory bowel diseases (IBD), lupus, macular degeneration (diabetic and age-related macular degeneration), malnutrition, Meniere’s disease, multiple sclerosis, Myasthenia Gravis, neurodegenerative diseases, nutritional disorders, Parkinson’s disease, primary biliary cirrhosis, progeria, psoriasis,rheumatic fever, sarcoidosis, scleroderma, shingles, stroke, surgery, toxic poisoning, trauma, vasculitis, vitiligo, Wegener’s Granulomatosis, to name a few.
Q. Has therapy to increase glutathione levels been effective in treating the diseases or
conditions that have been associated with low glutathione levels?
A. Yes. There have been many thousands of research studies proving that raising glutathione levels is an effective treatment in dozens of diseases and conditions. Of course, prevention is always a more desirable path.Immunocal/HMS9 0 has been proven to raise and maintain healthy levels of glutathione.
I apologize for the Length of this Post but, I wanted to get as much information out as possible. I will be adding to this subject as I know this product is the sole reason, other than God, that I have recovered from Kidney Cancer!!